Chemical tumor meningitis: Difference between revisions
(Created page with "'''Chemical tumor meningitis''' is defined here as meningeal inflammation secondary to the release of the contents of a cystic tumor into the subarachnoid spaces. The primary tumors found are usually benign (e.g. (epi)-dermoid cysts, craniopharyngiomas, etc.). The clinical picture is dominated by a meningeal syndrome and frequently spinal pain associated with bilateral or tilting radicular pain. It may evolve as a chronic or acute recurrent disease. Examination of cer...") |
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The primary tumors found are usually benign (e.g. (epi)-dermoid cysts, craniopharyngiomas, etc.). | The primary tumors found are usually benign (e.g. (epi)-dermoid cysts, craniopharyngiomas, etc.). | ||
The clinical picture is dominated by a meningeal syndrome and frequently spinal pain associated with bilateral or tilting radicular pain. It may evolve as a chronic or acute recurrent disease. | The clinical picture is dominated by a meningeal syndrome and frequently spinal pain associated with bilateral or tilting radicular pain. Fatal cases have been described, but are considered exceptional. It may evolve as a chronic or acute recurrent disease. | ||
Examination of cerebrospinal fluid (CSF) under polarized light may reveal keratin debris and/or cholesterol crystals, sometimes with elevated proteinorachy. Cerebral MRI usually reveals the causative lesion. | Examination of cerebrospinal fluid (CSF) under polarized light may reveal keratin debris and/or cholesterol crystals, sometimes with elevated proteinorachy. Cerebral MRI usually reveals the causative lesion. | ||
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Osborn AG, Diagnostic imaging : brain, Amirsys, USA, 2d ed., 2009 | Osborn AG, Diagnostic imaging : brain, Amirsys, USA, 2d ed., 2009 | ||
Pradat PF, Méningites chroniques, Encycl Méd Chir (Elsevier), Neurologie, 17-160-C-30, 2002{{Lien français|Article=Méningites chimiques tumorales}} | Pradat PF, Méningites chroniques, Encycl Méd Chir (Elsevier), Neurologie, 17-160-C-30, 2002{{Lien français|Article=Méningites chimiques tumorales}}{{Lien espagnol|Article=Meningitis tumoral química}} | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Neurology]] | [[Category:Neurology]] | ||
[[Category:Neuro-oncology]] | [[Category:Neuro-oncology]] | ||
Latest revision as of 15:17, 6 October 2023
Chemical tumor meningitis is defined here as meningeal inflammation secondary to the release of the contents of a cystic tumor into the subarachnoid spaces.
The primary tumors found are usually benign (e.g. (epi)-dermoid cysts, craniopharyngiomas, etc.).
The clinical picture is dominated by a meningeal syndrome and frequently spinal pain associated with bilateral or tilting radicular pain. Fatal cases have been described, but are considered exceptional. It may evolve as a chronic or acute recurrent disease.
Examination of cerebrospinal fluid (CSF) under polarized light may reveal keratin debris and/or cholesterol crystals, sometimes with elevated proteinorachy. Cerebral MRI usually reveals the causative lesion.
Prognosis and treatment depend on the nature of the tumour (simple excision in the case of benign tumours).
Author(s)
Dr Shanan Khairi, MD
Bibliography
Bradley WG et al., Neurology in clinical practice, 5th ed., Butterworth-Heinemann, e-dition, 2007
Cambier J et al., Neurologie, 13e édition, Masson, 2012
Osborn AG, Diagnostic imaging : brain, Amirsys, USA, 2d ed., 2009
Pradat PF, Méningites chroniques, Encycl Méd Chir (Elsevier), Neurologie, 17-160-C-30, 2002